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问与答

VAXXITEK® HVT + IBD疫苗有什么作用?

VAXXITEK HVT + IBD能预防马立克氏病(和HVT毒株一样)和传染性法氏囊(IBD;也称为甘保罗病)。

为什么接种马立克病和IBD疫苗非常重要?

它们是家禽中最常见、最主要的两种免疫抑制病毒性病,会导致发病、死亡、生长不良、生产性能低下。IBD和马立克氏病是无法治愈的,但接种疫苗能帮助预防疾病。

关于VAXXITEK HVT + IBD疫苗和各种IBD毒株,我们应该知道些什么?

目前已发表的超过65篇科学论文 (查看所有)表明,VAXXITEK HVT + IBD疫苗能对全球发现的多种不同的致病型IBD病毒起到临床保护的作用,包括经典型、变体型和超强型毒株。*

我们现在没有面临 IBD风险,我们为什么需要使用VAXXITEK HVT + IBD疫苗?

IBD在世界各地成地方流行,且传染性很强,常常会出现新的毒株,可能会随时发生。由于IBD无法治愈,预防便变得至关重要。此外,该疾病还可能存在亚临床感染,导致较高的免疫抑制,即使在没有明显的发病迹象的情况下也会导致鸡群表现不良和经济损失。16-17 多篇已发表的研究已经证明,在帮助预防IBD和马立克氏病的同时,VAXXITEK HVT + IBD疫苗也能帮助降低这种免疫抑制的潜在风险,为您的家禽健康打下坚实的免疫基础。5-8, 13-15, 31

VAXXITEK HVT + IBD疫苗安全吗?会导致法氏囊损伤吗?

多项研究已经证明VAXXITEK HVT + IBD有很好的安全性,有强效预防IBD的同时,还能够保护法氏囊的完整性,不会导致肉眼可见的法氏囊损伤,且镜下病变轻微。 10-12 部分原因是因为该疫苗使用了载体技术,不需要使用IBD全病毒。

VAXXITEK HVT+IBD疫苗是如何起作用的?

通过使用载体技术,一针 VAXXITEK HVT + IBD疫苗就能对两种疾病产生免疫作用——马立克氏病和IBD 。它所使用的作用方式无需计算IBD的疫苗接种日期,而是一种简单直接的疫苗接种方案。

哪种企业可以使用VAXXITEK HVT + IBD疫苗?

所有养鸡场都能使用VAXXITEK HVT + IBD疫苗。它能被用于健康的肉鸡、蛋鸡和种鸡。* 当前,该疫苗已在75个国家注册上市(以VAXXITEK HVT + IBD 作为商品名),其他市场的批准文书也在准备当中。如果您不确定在您的国家是否有售VAXXITEK HVT + IBD疫苗,请

VAXXITEK HVT +IBD疫苗会如何影响家禽的生产性能或企业产能?

通过预防IBD和马立克氏病,无数已发表的研究已经表明VAXXITEK® HVT + IBD疫苗能帮助家禽企业提高生产性能,因为更低疾病压力的家禽表现出更高的免疫健康状态,在多项参数方面有更优良的表现,如增重、5-7 、饲料转化率5, 7 、均匀度5等等。

VAXXITEK HVT + IBD疫苗的接种方式是什么?

疫苗在孵化场的良好的孵化场使用,或胎内(孵化18-19天时)注射,或对健康的1日龄鸡雏进行皮下注射。

我们企业如何没有进行孵化场接种,怎么办?

孵化场接种疫苗能免除现场接种疫苗相关的劳力和不确定性,是值得投资的。梅里亚会为您提供帮助。我们行业领先的接种技术与服务(VTS)团队将帮助您渡过整个过渡期,提供审计和现场准备计划、设备以及培训等等。

除疾病控制之外,VAXXITEK HVT + IBD疫苗还有哪些优势?

VAXXITEK HVT + IBD疫苗通过在孵化场进行单剂量的IBD疫苗接种,可以降低劳动量,加大对疫苗接种过程的监控,提高准确度。有证据证明,它对许多家禽企业都拥有很高的价值,能提高其成本效益。

VAXXITEK HVT + IBD疫苗会导致现场病毒扩散或传染吗?

VAXXITEK HVT + IBD疫苗仅使用IBD病毒的VP-2蛋白(VP2)(而非IBD全病毒),诱导机体产生对IBD的免疫保护。接种VAXXITEK HVT + IBD疫苗不会给家禽注入IBD全病毒,因此不会导致环境中的排毒。3 为预防马立克氏病,VAXXITEK HVT + IBD疫苗使用火鸡疱疹病毒(HVT),这是一种为人熟知的能刺激对马立克氏病的免疫,同时本身对雏鸡无致病性的病毒。此外,一篇已发表的研究表明,长期在现场使用VAXXITEK HVT + IBD疫苗总体上会降低IBD病毒的威胁。24

存在母源抗体时, VAXXITEK HVT + IB疫苗有何表现?

VAXXITEK HVT + IBD疫苗仅通过使用IBD病毒的VP-2蛋白(而非IBD全病毒),诱导机体产生对IBD的免疫保护。通过使用火鸡疱疹病毒(HVT)促进对马立克氏病的免疫。已出版的研究中已经证明,雏鸡的母源抗体对IBD VP2和HVT只有极小的干扰。12这意味着可以尽早使用VAXXITEK HVT + IBD疫苗(孵化18-19天时在鸡胚胎内注射,或对健康的1日龄鸡雏进行皮下注射)以增强免疫力,从而在母源抗体下降时逐渐产生作用。12

我们如何使用VAXXITEK HVT + IBD疫苗以优化我们的疫苗接种程序?

混合免疫多种疫苗可能会导致不良反应,从而降低疫苗效力。一般而言,使用多种疫苗制定家禽健康程序是一项非常复杂的工作,需要专业的知识,所以我们建议您咨询我们的兽医服务团队。他们能根据您的业务和特定的疾病需求,帮助您和您的兽医团队量身定制一套孵化场免疫程序,以VAXXITEK HVT + IBD疫苗为基础,为您的家禽健康奠定坚实的免疫基础。

接种VAXXITEK HVT + IBD疫苗后能现场测量或评估免疫原性吗?

当前的技术允许监控鸡雏接种 VAXXITEK HVT + IBD疫苗后的情况,以评估IBD免疫性。18 我们也提供诊断工具用以区分被野毒感染了的雏鸡和接种了VAXXITEK HVT + IBD疫苗的鸡雏,且药效超出预想的雏鸡。19我们的兽医服务团队帮助您和您的企业解决这个问题。
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参考文献

查看所有

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22. Jay ML, Bizzini S, Duboeuf M, Goutebroze S, Le-Gros FX. Compatibility of a novel vector vaccine HVT-Gumboro with Newcastle and infectious bronchitis vaccination at one day of age. Abstract. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p341.

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32. Lemiere S, Bublot M, de Saint-Vis B, Le-Gros FX, Dancer A, Bollart A, Carlotti A. Validation of VAXXITEK HVT+IBD vaccine intake in chickens using vHVT13-specifi c qPCR by processing different tissue samples. Oral presentation. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p165.

33. Rautenschlein S, Simon B, Jung A, Pöppel M, Prandini F, Lemiere S. Protective efficacy of VAXXITEK HVT + IBD in commercial layers and broilers against challenge with very virulent infectious bursal disease virus. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009.