Celebrating 10 years of protection

VAXXITEK® HVT + IBD

Merial's advanced vector vaccine for the poultry industry.

Just one shot at the hatchery provides two-in-one protection against IBD and Marek's disease - among the most serious immunosuppressive poultry diseases - in broiler, layer and breeder chickens.*

Innovation from animal health leader Merial, a Sanofi company.

 

Global Protection. Individual Solutions.

The VAXXITEK HVT + IBD solutions package: Protection against Marek’s disease and IBD—in 65+ scientific papers published to date (see all), it induced clinical protection against many different classic, variant, and very virulent IBD strains.* Plus, Merial’s customized services for integration into your vaccination program and business operations.

Simplify your operations with…

A single injection at the hatchery. No need to calculate maternal antibodies or vaccination dates. The peace of mind that comes from accurate, reliable hatchery administration. Merial's state-of-the-art vaccination equipment and industry-leading support services.

What you don’t see may hurt your business

Sub-clinical forms of IBD exist that have few outward disease signs—but still cause significant immunosuppression and poor performance.5, 16-17 Several published studies have demonstrated that by preventing IBD and Marek's disease, VAXXITEK HVT + IBD fights this hidden threat and helps you lay a strong immune foundation for flock health.5-8, 13-15, 31

Healthy flock today. Healthy business tomorrow.

By aiding in the prevention of IBD and Marek’s disease, VAXXITEK® HVT + IBD may help poultry businesses perform better across several key parameters. Studies and customers attest: flocks with a lower disease burden also often demonstrate better weight gain1-3, feed conversion ratios1, 3, uniformity1,3 and more.

Savings in carcass condemnations: ~$175,000 (USD)

One Brazilian study found that because they were protected against IBD and Marek’s disease and had a reduced disease burden, VAXXITEK HVT+IBD-treated broiler birds had lower carcass condemnation rates—which resulted in economic savings  at the processing plant.4

When VAXXITEK® HVT + IBD started to function, it exceeded all my expectations.
DR. Fernando Galindo RamírezGrupo Avicola Romero, Mexico

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

The VAXXITEK® HVT + IBD group had better body weight as well as better livability, and also the size of the bursa was more ideal.
Chong Tau Yeng Gesing Group Sdn Bhd, Malaysia

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

VAXXITEK® HVT + IBD was a very important factor, helping us achieve better feed conversion, spend less on food, and produce greater amounts of meat.
Dr. Irineu Dantes PeronCopacol, Brazil

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

With VAXXITEK® HVT + IBD the company saved 7 cents per kg of meat.
Dr. Alberto BoteroAvidesa MacPollo, Colombia

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

The production parameters increased considerably—about 15-20 points of EPEF.
Joszef PalagyiHungary

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

Saving time, getting home a bit earlier, is not such a bad thing! No VAXXITEK® HVT + IBD would be bad news; it would be a step back.
Christian ChatardFrance. Also in this video: Dr. Chabrol & Mr. Marquis

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

After the impressive results we got, we decided to expand the use of VAXXITEK® HVT + IBD in our company—in the last 4 years we’ve used over 300 million doses.
Li Wen Ji, Vice President & Chief VeterinarianFujian Sunner Group, China

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

The views expressed are of the customer. VAXXITEK® HVT + IBD is indicated to aid in the prevention of Marek’s and infectious bursal diseases; it may help poultry businesses improve productivity because flocks with lower disease burden often perform better across key production parameters.

How can we help you?

More than just a product: a partnership, programs, tools, and resources to help you maximize your business potential.

THE VAXXITEK HVT + IBD SOLUTIONS PACKAGE

Get IBD and Marek's disease protection for your flock, backed by a trusted service partner to deliver customized, on-site support for your avian health needs.

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SCIENTIFIC LITERATURE

Explore our selection of the most important publications on studies and trials from around the world, evaluating VAXXITEK HVT + IBD across a range of metrics and scenarios.

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JOIN OUR E-LEARNING COMMUNITY

Access our interactive online module, to learn more about VAXXITEK HVT + IBD and other key issues in the poultry industry.

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TELL US WHAT YOU NEED...

More information on VAXXITEK HVT + IBD? A strategy for integrating it into your operations? Industry insights? Drop us a line and let’s talk more.

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Referenced Publications

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1. Fernandez R, Rojo F, Garcia H, Sanchez P, Martinez H, Menendez A, Ruiz H et al. Field efficacy in broiler chickens in Latin America of vHVT-013, a Marek’s HVT vector vaccine expressing VP2 in infectious bursal disease virus. Oral presentation and abstract at the 15th congress of the World Veterinary Poultry Association, 2007; p199.

2. Atienza JC, Nagera AJ, Martinez PO, Baysac ND, Castillo MT, Damaso VR, Lemière S. Evaluation of a herpesvirus of turkey vector vaccine inducing protection against infectious bursal and Marek’s diseases (VAXXITEK® HVT+IBD) under Philippines field conditions. Oral presentation. XXIII World Poultry Congress, Brisbane, Australia. 2008. Article wpc0801684, 9 p.

3. Garritty AT. The eff ect of vectored HVT+IBD (Vaxxitek® HVT + IBD) vaccination on body weights, uniformity and virus shedding in commercial broilers. Abstract. International Poultry Scientifi c Forum, Atlanta, 2011; p31.

4. Godinho E, Pereira CJ, Fernandez A, Lemiere S. Case study of broiler chicken carcass condemnation in Brazil – Improved control using a herpesvirus turkey-infectious bursal disease (HVT-IBD) vector vaccine. Oral presentation. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011.

5. Hoerr FJ. Clinical Aspects of Immunosuppression in Poultry. Avian Dis., 2010; 54:2-15.

6. Naqi S, Thompson G, Bauman B, Mohammed H. The Exacerbating Effect of Infectious Bronchitis Virus Infection on the Infectious Bursal Disease Virus-Induced Suppression of Opsonization by Escherichia coli Antibody in Chickens. Avian Dis., 2001; 45:52-60.

7. Alonso Castro M, Merino Cabria D, Fernandez Garcia D, Torrubia Diaz J, Herreras Viejo R, Fernandez Revuelta J, Mateo Oyague J, Carvajal Uruena A. Evaluation of the effects of vaccination with a HVT-IBD vector vaccine on bursa Fabricii, production parameters and meat properties in broilers. Abstract. XVIIIth Congress of the World Veterinary Poultry Association, Nantes, France, 2013; in-press.

8. Devaud I, Herin JB, Trotel A, Pagot E, Voisin F. A field study in commercial layers to evaluate the effects of an HVT-IBD vector vaccine on production performances in comparison with a live IBD vaccine. Abstract. XVIIIth Congress of the World Veterinary Poultry Association, Nantes, France, 2013; in-press.

9. Lemiere S, Gauthier J.C., Kodjo A., Vinit L., Delvecchio A., Prandini F. Evaluation of the Protection against Infectious Bursal Disease (IBD) Challenge in Progeny Born to Parents Having Received a Vaccination Program Using Herpesvirus of Turkey-Infectious Bursal Disease (HVT-IBD) Vector Vaccine. World J. Vaccines, 2013; 3:46-51.

10. Goutebroze S, Curet M, Jay ML, Roux C, Le Gros F-X. Efficacy of a recombinant vaccine HVT-VP2 against Gumboro disease in the presence of maternal antibodies. British Poultry Science, 2003;44:824-825.

11. Massi P, Tosi G, Fiorentini L. Experimental challenge trial with a «very virulent» strain of Infectious Bursal Disease virus (vvIBDV) in commercial pullets vaccinated with an IBD vectored vaccine or with three different modified live vaccines. Zootecnica International, November 2008;50-57.

12. Bublot M, Pritchard N, Le Gros F-X, Goutebroze S. Use of a vectored vaccine against infectious bursal disease of chickens in the face of high-titred maternally derived antibody. Journal of Comparative Pathology, 2007;137:81-84.

13. Ganapathy K, Wilkins M, Forrester A, Jones RC, Lemiere S. Protection and immune responses against virulent infectious bronchitis viruses in HVT-IBD recombinant or IBD-complex vaccinated broiler chicks. Abstract. 1st International Respiratory Disease Conference, Athens, United States of America, 2011; p15.

14. Lemiere S, Wilkins M, Forrester A, Jones R, Ganapathy K. Protection and immune responses against virulent infectious bronchitis (IB) viruses in herpesvirus turkey-infectious bursal disease (HVT-IBD) vaccinated broiler chicks. Poster presentation. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011.

15. Rautenschlein S, Lemiere S, Prandini F. Evaluation of the effects of an HVT-IBD vector vaccine on the immune system of layer pullets in comparison with two commercial live IBD vaccines. Abstract. XVIIIth Congress of the World Veterinary Poultry Association, Nantes, France, 2013; in-press.

16. Rosenberger JK, Cloud SS. Identification and characterization of variant infectious bursal disease variant viruses. Journal of American Veterinary Medicine Association, 1986;189:357.

17. Cheville NF. Studies on the pathogenesis of Gumboro disease in the bursa of Fabricius, spleen and thymus of the chicken. American Journal of Pathology, 1967;51:527-551.

18. Le Gros F-X, Dancer A, Giacomini C, Pizzoni L, Bublot M, Graziani M, Prandini F. Field efficacy trial of a novel HVT-IBD vector vaccine for 1 day-old broilers. Vaccine, 2009;27:592-596.

19. Prandini F, Bublot M, Le Gros F-X, Dancer A, Pizzoni L, Lamichhane C. Assessment of the immune response in broilers and pullets using two ELISA lits after in ovo or day-old vaccination with a vectored HVT+IBD vaccine (VAXXITEK HVT+IBD). Zootecnica International, September 2008;40-50.

20. Lemiere S, Wong YS, Saint-Gerand AL, Goutebroze S, le Gros FX. Compatibility of Turkey Herpesvirus–Infectious Bursal Disease Vector Vaccine with Marek’s Disease Rispens Vaccine Injected into Day-Old Pullets. Avian Dis., 2011; 55:113-118.

21. Richard-Mazet A, Goutebroze S, Duboeuf M, Le Gros FX, Lemiere S, Bublot M. Compatibility of fowlpox-avian influenza and herpesvirus of turkey-infectious bursal disease vector vaccines injected in ovo to embryonated chicken eggs. Article. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011; p852-857.

22. Jay ML, Bizzini S, Duboeuf M, Goutebroze S, Le-Gros FX. Compatibility of a novel vector vaccine HVT-Gumboro with Newcastle and infectious bronchitis vaccination at one day of age. Abstract. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p341.

23. Lemiere S, Fernandez R, Pritchard N, Cruz-Coy J, Rojo F, Wong SY, Saint-Gerand AL, Gauthier JC, Perozo F. Concomitant Turkey Herpesvirus–Infectious Bursal Disease Vector Vaccine and Oil-Adjuvanted Inactivated Newcastle Disease Vaccine Administration: Consequences Compatibility of Turkey Herpesvirus–Infectious Bursal Disease. Avian Dis., 2011; 55:642-649.

24. Botero LA, Fernandez R, Rojo F, Orrego JC, Lemiere S. Colombian chicken meat industry performance further to the use of VAXXITEK HVT+IBD vector vaccine. Oral presentation. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p169.

25. Körösi L, Povazsan J, Penzes L, Sari I. Field results of VAXXITEK HVT+IBD vaccination in coloured birds in Hungary. Poster. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p339.

26. Tang SF, He SJ, Li WM, Lemiere S. Field experience of vaccination in day-old broiler chickens with a herpesvirus turkey-infectious bursal disease (HVT-IBD) vector vaccine in different systems of chicken production across China. Poster presentation. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011; p920-926.

27. Herrmann A, Negm H, Sultan H. Turkey herpesvirus infectious bursal disease (HVT-IBD) vector vaccine – Field experience in commercial broilers in Egypt. Article. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011; p556-563.

28. Ochoa R. Monitoring of safety and efficacy of a herpesvirus turkey-infectious bursal disease (HVT-IBD) in a commercial layer operation in Mexico. Article. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011; p770-774.

29. Korosi L, Povazsan J, Sari I, Penzes L. Comparative field study of the Vaxxitek® HVT-IBD vaccine in commercial layer flocks. Article. XVIIth Congress of the World Veterinary Poultry Association, Cancun, Mexico, 2011; p644-650.

30. Lemiere S, Rojo R, He S, Tang S, Li W, Herrmann A, Prandini F. Benefits of the Herpesvirus of Turkey vector vaccine of Infectious Bursal Disease in control of immune-depression in broilers and decrease of use of antibiotic medication. Abstract. XVIIIth Congress of the World Veterinary Poultry Association, Nantes, France, 2013; in-press.

31. Rautenschlein S, Lemiere S, Simon B, Prandini F. A comparison of the effects on the humoral and cell-mediated immunity between an HVT-IBD vector vaccine and an IBDV immune complex vaccine after in ovo vaccination of commercial broilers. Article. XVIIth Congress of the World Vet.

32. Lemiere S, Bublot M, de Saint-Vis B, Le-Gros FX, Dancer A, Bollart A, Carlotti A. Validation of VAXXITEK HVT+IBD vaccine intake in chickens using vHVT13-specifi c qPCR by processing different tissue samples. Oral presentation. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009; p165.

33. Rautenschlein S, Simon B, Jung A, Pöppel M, Prandini F, Lemiere S. Protective efficacy of VAXXITEK HVT + IBD in commercial layers and broilers against challenge with very virulent infectious bursal disease virus. 16th congress of the World Veterinary Poultry Association, Marrakesh, Morocco, 2009.